Visual Basic.NET - datagrid

hola, necesito cargar un datagrid para desplegar datos de una consulta.

tengo el siguiente codigo y nose datos o objeto tengo que pasr al data
para que me despliege los datos

Dim myConnection As SqlConnection
Dim mySqlDataAdapter As SqlDataAdapter

myConnection = New SqlConnection("data source=JORDAN-EFACTURA;initial catalog=northwind;UID=sa;pwd=123;")
mySqlDataAdapter = New SqlDataAdapter("Select * from Region", myConnection)

por cualquier ayuda muchas gracias....

ejemplo en vb.net....
imports sytem.data.sqlclient
......
Inherits System.Windows.Forms.Form
Private conn As sqlConnection
Private DA As sqlDataAdapter
Private CB As sqlCommandBuilder
Private DS As DataSet

Private Sub Form1_Load(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles MyBase.Load
conn = New OleDbConnection("server=(local);trusted_connection=yes;database=empresa")
DA = New sqlDataAdapter("select * from tbl_empleados", conn)
CB = New sqlCommandBuilder(DA)
DS = New DataSet()
DA.Fill(DS, "empleados")
Me.DataGrid1.DataSource = DS
Me.DataGrid1.DataMember = "empleados"